##  simulateDatExpr: simulating 500 genes in 5 modules.
##  simulateDatExpr: simulating 500 genes in 5 modules.
##            truemodule1
## truemodule0   0   1   2   3   4   5
##           0 125   0   0  75  75   0
##           1   0  75   0   0   0   0
##           2   0   0  75   0   0   0
##           5   0   0   0   0   0  75
## [1] 100 500
## TOM calculation: adjacency..
## adjacency: replaceMissing: 0
## ..will not use multithreading.
##  Fraction of slow calculations: 0.000000
## ..connectivity..
## ..matrix multiplication..
## ..normalization..
## ..done.
## TOM calculation: adjacency..
## adjacency: replaceMissing: 0
## ..will not use multithreading.
##  Fraction of slow calculations: 0.000000
## ..connectivity..
## ..matrix multiplication..
## ..normalization..
## ..done.
## TOM calculation: adjacency..
## adjacency: replaceMissing: 0
## ..will not use multithreading.
##  Fraction of slow calculations: 0.000000
## ..connectivity..
## ..matrix multiplication..
## ..normalization..
## ..done.

Heatmaps of Correlations

All

E=0

E=1

E=1 - E=0

\(S = |\rho_{E=0} + \rho_{E=1} - 1.5 \rho|\)

Fisher’s Z Statistic

Heatmaps of TOM

All

E=0

E=1

E=1 - E=0

\(S = |TOM_{E=0} + TOM_{E=1} - 1.5 TOM|\)